R. Singh, N. K. Mishra, V. Kumar, V. Vinayak, and K. B. Joshi, ChemBioChem. 2018, 19, 1630-1637. https://doi.org/10.1002/cbic.201800220 Very Important Paper (VIP) Media Cover Chemistry View


Biomolecular switches: A palmitoylated bis-tyrosine-based short-peptide amphiphile (sPA) transforms its morphology in the presence of bioactive transition-metal ions. The metal-ion-conjugated sPA hybrid nanostructures were effective against Gram-positive bacteria. It was found that the designed sPA was greatly taken up by bacteria and therefore acted as a cytotoxic metal ion delivery agent. 

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